It provides the framework for thinking about these decisions in ways that are fair and equitable. This encompasses issues related to who benefits from research and who bears the risks of research. Researchers designing trials should consider what is fair in terms of recruitment of participants and choice of location to conduct a trial. This principle deals with the concept of fairness. Researchers are obligated to do their best to minimize those possible risks and to maximize the benefits for participants. This means participants may be exposed to some harms or risks. The purpose of much research involving humans is to show whether a drug is safe and effective. Maximize benefits for participants and minimize risks for participants The purpose of research should never be to hurt anyone or find out information at the expense of other people. The purpose of health research is to discover new information that would be helpful to society. This principle states that research should: The definition of beneficence is action that is done for the benefit of others. In such cases, these people should be protected and only be included in research under specific circumstances, since they cannot make a true informed decision on their own. This could include young children, people who are very ill, or those with mental disabilities. Some people in society may not have the capacity to make fully informed decisions about what they do or what happens to them. People with diminished autonomy should be protected In order to treat people as autonomous, individuals must be provided with complete information about a study and decide on their own whether to enroll. Researchers must respect that individuals should make their own informed decisions about whether to participate in research. The term autonomous means that a person can make his or her own decisions about what to do and what to agree to. This principle incorporates two elements that deal with respecting people in regard to research: Research ethics are based on three fundamental principles.
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